Glossary (Non - Technical):
Here is a list of terms used
by the medical community. We have tried to offer it in layman's language.
We all know how doctors love to use those technical names and phrases.
accessible - tumors
which can be approached by a surgical procedure, not deep in the brain
or beneath vital structures.
alopecia - loss of hair;
baldness in areas where hair is usually present. A common side effect
of radiation therapy to the brain and some chemical therapies.
anaplasia - characteristics
of a cell identifies it as a cancer cell. Malignant.
angiogram - a diagnostic
procedure done in the x-ray department to visualize blood vessels following
introduction of a contrast material into an artery.
anosmia - absence of
the sense of smell. Symptom common to tumors of the frontal lobe of the
cerebral hemispheres.
aphasia - loss of ability
to speak or write; loss of ability to understand speech or written words.
benign - not malignant.
biopsy - examination
of a small amount of tissue taken from the patient's body to make a diagnosis.
cancer - malignant tissue
that is invasive, destroys healthy tissue, and tends to spread to distant
locations.
carcinoma - a malignant
tumor that arises from epithelium, found in skin and the lining of body
organs; for example, breast, prostate, lung, stomach or bowel. Carcinomas
tend to infiltrate into adjacent tissue and spread (metastasize) to distant
organs, such as bone, liver, lung, or the brain.
catheter - a flexible,
tubular instrument, used for the removal or insertion of fluids.
cerebral - referring
to the cerebrum, part of the brain.
cerebrospinal fluid -
the clear fluid made in the ventricular cavities of the brain that bathes
the brain and spinal cord.
cerebrum - the largest
area of the brain, the cerebrum occupies the uppermost part of the skull.
It consists of two halves called hemispheres. Each half of the cerebrum
is further divided into four lobes: frontal, temporal, parietal and occipital.
chemotherapy - the use
of chemical agents to treat brain tumors.
circumscribed - having
a border, localized. Often associated with a capsule and benign tumors
of the brain: meningiomas, pituitary adenomas and acoustic neuromas.
congenital - existing
before or at birth.
contralateral - affecting
the opposite side.
cranial cavity - the
skull.
craniectomy - surgery
performed on the skull where pieces of bone are removed to gain access
to the brain, and the bone pieces are NOT replaced.
craniotomy - surgery
performed on the skull where a portion of bone is removed to gain access
to the brain, and the bone is PUT BACK in its place.
CT or CAT scan Computerized
Axial Tomography - an x-ray device linked to a computer that produces
an image of a predetermined cross-section of the brain. A special dye
material may be injected into the patient's vein prior to the scan to
help make any abnormal tissue more evident.
cyst - a fluid filled
mass. Usually enclosed by a membrane.
debulk - a surgical
procedure to decrease swelling by removing a portion of a tumor or dead
tissue.
Decadron (R) - Dexamethasone.
A glucocorticosteroid medication used to reduce brain tissue swelling.
decompressive - surgical
procedure during which bone, tissue, or tumor is removed to lessen intracranial
pressure.
diabetes insipidus -
a problem with water balance in the body causing excess urine production
and great thirst, due to pituitary-hypothalamic damage in the brain. Ordinary
diabetes, which has the same symptoms, is due to insufficient insulin
production by the pancreas.
diplopia - double vision.
distal - located far
from the reference point.
dura mater - the outermost,
toughest, and most fibrous of the three membranes (meninges) that cover
the brain and spinal cord.
dysarthria - impairment
of speech caused by damage or disorder of the tongue or speech muscles.
Symptom may indicate pressure on the brain stem or elsewhere.
dysphagia - difficulty
in swallowing or inability to swallow. Symptom usually indicates tumors
involving the lower brain stem.
dysphasia - language
disorder. Inability to speak words which one has in mind or to think of
correct words; or inability to understand spoken or written words. Symptom
common to tumors of the dominant cerebral hemisphere, particularly the
frontal, temporal, and parietal lobes.
edema - swelling due
to an excess of water.
encapsulated - tumor
that is wholly confined to a specific area, surrounded by a capsule. Localized.
endoscope - a slender,
tubular instrument used to examine the interior of a body cavity.
etiology - the study
of the cause of a disease.
evoked potentials -
the use of electrodes to measure the electrical activity of nerves. May
be used as a guide during the removal of tumors growing around the important
nerves.
extracerebral - located
outside the cerebral hemispheres.
extradural - located
outside the dura mater.
gait - pattern of walking.
ganglia - a mass of
nerve tissue (gray matter) or a group of nerve cell bodies. Also refers
to specific groups within the brain or spinal cord (as basal ganglia).
Ganglion is the singular of ganglia.
glucocorticosteroids -
medications used to decrease swelling around tumors.
gray matter - the "thinking
brain" appears gray because it is composed of numerous nerve cells and
blood vessels. The outer layer of the cerebrum - the cerebral cortex,
and areas deep within the brain - the basal ganglia, are made up of gray
matter.
growth factor - a naturally
occurring protein chemical that stimulates cell division and proliferation.
It is produced by normal cells during embryonic development, tisue growth,
and wound healing. Tumors, however, produce large amounts of growth factors.
hemianopsia - loss of
one half of the field of vision (the area that can be seen by each eye
when staring straight ahead).
hemiparesis - muscle
weakness of one side of the body.
hemiplegia - complete
paralysis of one side of the body.
herniation - bulging
of tissue through an opening in a membrane, muscle or bone.
heterogeneous - composed
of various cell types.
homogeneous - composed
of identical cell types.
hydrocephalus - Hydro
= water, cephalo = head. Excess water in the brain due to blockage of
cerebrospinal fluid flow, increased production, or decreased absorption.
hyperfractionation -
an increased number of smaller dosage treatments of radiation.
hyperthermia - the use
of heat to kill tumor cells.
hypophysis - pituitary
gland.
hypotonicity - diminished
muscle tone; limp muscles.
ICP -IntraCranial Pressure
- harmful when increased.
immunotherapy - use
of the body's immune system to fight tumors.
infiltrating - tumor
that penetrates the normal, surrounding tissue.
informed consent - the
right to have information explained to you so that you fully understand
and agree to the nature of the proposed treatment.
interstitial radiation therapy
- the implantation of radioactive seeds directly into a tumor.
intra-arterial - injection
into an artery (that may supply a tumor).
intracerebral - located
within the cerebral hemispheres (cerebrum).
intracranial - within
the skull.
intradural - beneath
the dura mater.
intramuscular - into
a muscle.
intrathecal - injection
into the sub-arachnoid space of the meninges. Usually done by lumbar puncture.
intratumoral - injection
into a tumor (usually performed during surgery).
intravenous - injection
into a vein.
intraventricular - injection
into a ventricle.
invasive - refers to
a tumor that invades healthy tissues. The opposite of encapsulated. Also
called diffuse or infiltrating.
ipsilateral - affecting
the same side.
irradiation - treatment
by ionizing radiation, such as x-rays, or radioactive sources such as
radioactive iodine seeds.
laser - an acronym of
light amplification by stimulated emission of radiation. A surgical tool
that creates intense heat and power when focused at close range, destroying
cells by vaporizing them.
local - in the area
of the tumor, confined to one specific area.
lumbar puncture - spinal
tap. Needle penetration into the subarachnoid space of the lumbar spine.
Used to withdraw a sample of spinal fluid for examination. Also used to
inject a dye into the spine prior to a myelogram.
malignant - cancerous
or life-threatening, tending to become progressively worse.
membrane - thin layer
of tissue covering a surface, lining a body cavity, or dividing a space
or organ.
metastisize - to spread
to another part of the body, usually through the blood vessels, lymph
channels, or spinal fluid.
monoclonal antibodies (MAB)
- a biological response modifier with unique "homing device" properties.
Chemicals or radiation tagged to the MAB may be delivered directly to
tumor cells. Or, the MAB itself may be capable of tumor cell destruction.
MRI scan Magnetic Resonance
Imaging - a scanning device that uses a magnetic field, radio waves, and
a computer. Signals emitted by normal and diseased tissue during the scan
are assembled into an image.
necrosis - dead cells.
A common feature of glioblastoma multiforme and other malignant tumors,
including metastatic cancer to the brain. Caused by either lack of blood
supply or irradiation.
neoplasm - a tumor,
either benign or malignant.
neuron - nerve cell;
conducts electrical signals.
nervous system - the
entire integrated system of nerve tissue in the body: the brain, brain
stem, spinal cord, nerves and ganglia.
nuclear medicine - the
branch of medicine that deals with the use of radioisotopes in therapy
and diagnosis.
nucleus - the center
of the cell containing the genetic information (genes, chromosomes, DNA,
etc.) The appearance of the nucleus is used as a criterion to determine
the malignant potential of a cell of tissue.
nystagmus - rapid movement
of the eyeballs.
Ommaya reservoir - a
device with a fluid reservoir implanted under the scalp with a catheter
to a ventricle. It allows for medication to be given directly to the CSF
(cerebrospinal fluid) and into the brain.
oncogene - fragments
of genetic material (DNA) that carry the potential to cause cancer (transform
normal cells into malignant cells).
oncogenesis - the causation
or production of tumors.
palsy - complete paralysis.
papilledema - swelling
of the optic nerve. Indicates increased intracranial pressure on the optic
nerve. Also called choked disc.
paresis - weakness.
paresthesia - abnormal
sensations, such as burning, prickling.
PET scan Positron Emission
Tomography - a scanning device which uses low-dose radioactive sugar to
measure brain activity. This is a limited-use diagnostic tool.
Phenobarbital (R) -
a sedating medication used to control seizures.
photodynamic radiation therapy
- a light sensitive drug which is given through a vein and concentrates
in the tumor. Then, during a surgical procedure, a special light activates
the drug. The activated drug kills the tumor cells.
PNET Primitive NeuroEctodermal
Tumor.
primary brain tumor -
original source of tumor which is the brain rather than other areas of
the body.
primitive - undeveloped
or in early stages of development, undifferentiated.
prognosis - a forecast
as to probable outcome.
proto-oncogenes - fragments
of genetic material (DNA), related to oncogenes, but are the normal "switches"
used to control growth and tissue repair.
proximal - located closest
to the reference point.
radiation therapy -
the use of radiation energy to interfere with tumor growth.
radioresistant - resistant
to radiation therapy.
radiosensitive - responsive
to radiation therapy.
recurrence - the return
of symptoms or the tumor itself, as opposed to a remission.
remission - the disappearance
of symptoms; the disappearance of the tumor.
resection - surgical
removal of a tumor.
residual - remaining
tumor.
respiration - breathing.
To inhale and exhale.
seizure - convulsions,
epilepsy, due to temporary disruption in electrical activity of the brain.
shunt - a drainage system.
Spinal fluid flows from a ventricle into a body cavity via a tube. Used
to relieve increased intracranial pressure caused by brain tumors that
block the flow of spinal fluid.
shunt (VA) ventriculo-atrial
- the tube empties into the right atrium of the heart.
shunt (VP) ventriculo-peritoneal
- the tube empties into the stomach.
spasticity - increased
involuntary muscle contraction (the opposite of hypotonicity).
stalk - a stem. Usually
refers to the pituitary stalk that connects the pituitary gland to the
hypothalamus.
stereotactic - precise
positioning in three dimensional space. Refers to surgery or radiation
therapy directed by scanning devices.
stereotactic radiosurgery
- a radiation therapy technique that uses a large number of narrow,
precisely aimed, highly focused beams of ionizing radiation. The beams
are aimed from many directions circling the head, and meet at a specific
point, the tumor.
strabismus - imperfect
eye coordination (crossed eyes).
subcutaneous - beneath
the skin.
systemic - circulating
throughout the body.
tinnitus - buzzing or
ringing in the ear. Symptom common to tumors of the acoustic nerve.
tumor marker - substances
found in blood or other fluids that identify the presence of a tumor,
and/or the tumor type.
ultrasound - visualization
of structures in the body by recording the reflections of sound waves
directed into tissues. May be used during surgery.
vascular - relating
to blood vessels.
vascularity - the blood
supply of a tumor.
vertigo - dizziness.
Symptom common to tumors of the acoustic nerve
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