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Introduction to SinusitisSinusitis affects about 14% of the population. Its direct medical costs amount to billions of dollars annually. Indirectly, its cost is greatly magnified by the staggering amount of lost hours of work or school. Current methods of cost analysis indicate that sinusitis usurps nearly 1% or the entire Gross National Product. Clinically, it is defined by physicians as a condition which is manifested by an inflammation involving the muscous membranes of the nasal cavity and the paranasal sinuses. The secretions found in these passages are related to the pathologic changes in both the surrounding bone and tissue. Sinusitis is classified as: Acute SinusitisAcute Sinusitis is sudden in onset and lasts up to 4 weeks. The symptoms resolve completely and, once the disease has been treated, antibiotics are no longer needed. A strong history consistent with acute Sinusitis includes two or more major factors or one major and two minor factors. However, the finding of nasal purulence is a strong indicator of an accurate diagnosis. A suggestive history for which acute Sinusitis should be included in the differential diagnosis includes one major factor or two or more minor factors. In the absence of other nasal factors, fever or pain alone does not constitute a strong history. Severe, prolonged, or worsening infections may be associated with a nonviral element. Factors suggesting acute bacterial Sinusitis are the worsening of symptoms after 5 days, the persistence of symptoms for more than 10 days, or the presence of symptoms out of proportion to those typically associated with a viral (upper respiratory) infection. Chronic SinusitisChronic Sinusitis is Sinusitis lasting as long as 12 weeks. The diagnosis is confirmed by the major and minor clinical factors complex described previsouly with or without findings on the physical examination. A strong history consistent with chronic Sinusitis includes the presence of two or more major factors or one major and two minor factors. A history suggesting that chronic sinusitis should be considered in the differential diagnosis includes two or more minor factors or one major factor. Facial pain does not constitute a strong history in the absence of other nasal factors. Cultures may be of particular value in identifying resistant microbial flora. Acute Exacerbation of Chronic SinusitisAcute exacerbation of chronic adult Sinusitis represents a sudden worsening of the baseline chronic Sinusitis with either worsening or new symptoms. Typically, the acute (not chronic) symptoms resolve completely between occurrences. Due to the underlying chronic nature of this condition, bacterial flora may represent resistant or atypical strains. Thus, endoscopically guided culture may be particularly helpful in directing antimicrobial therapy. Recurrent SinusitisRecurrent acute Sinusitis is defined by symptoms and physical findings consistent with acute Sinusitis, with these symptoms and findings worsening after 5 days or persisting as long as 10 days. However, each episode lasts 7 to 10 days or more and may last up to 4 weeks. Furthermore, as many as 4 episodes occur in 1 year. Between episodes, symptoms are absent without current antibiotic therapy. The diagnostic criteria for recurrent acute Sinusitis are otherwise identical to those for acute Sinusitis. Large Endoscopic views (click for larger picture):
Subacute SinusitisSubacute Sinusitis represents a continuum of the natural progression of acute Sinusitis that has not resolved. This condition is diagnosed after a 4-week duration of acute Sinusitis, and it lasts up to 12 weeks. Subacute Sinusitis is not known to represent a discrete histopathologic entity, but it may warrant therapy different from that for either acute Sinusitis or chronic Sinusitis. Patients with subacute Sinusitis may or may not have been treated for the acute phase, and the symptoms are less severe than in acute Sinusitis. Thus, unlike in acute Sinusitis, fever would not be considered a major factor. The clinical factors required for the diagnosis of subacute adult Sinusitis are the same for those for chronic Sinusitis. Subacute Sinusitis usually resolves completely after an effective medical regimen. Organism Based Classification
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